The Spring 2017 Biology Seminar Series commences with David W. Scott's talk, "Driving CARs to BARs: The road to engineered human antigen-specific regulatory and cytotoxic T cells."
The specificity of the immune system is powerful and has been harnessed in a novel therapy for cancer, called CARs (for Chimeric Antigen Receptors). Â Our lab has applied this approach to create regulatory police CARs that stop harmful immune responses in autoimmunity and hemophilia, and we have now driven them to BARs.